On the occasion of World Cancer Day, the Paris Saclay Cancer Cluster, announced by the French President Emmanuel Macron, in June 2021, is now organized as an association, whose purpose and ambitions were presented at Gustave Roussy Hospital, in the presence of Olivier Véran, Minister of Solidarity and Health, Frédérique Vidal, Minister of Higher Education, Research and Innovation and representatives of the five founding members: Sanofi, Gustave Roussy, Inserm, Institut Polytechnique de Paris and Université Paris-Saclay.