Engineering for Health Interdisciplinary Center (E4H)
Our society is undergoing a revolution that will fundamentally redefine our approach to the biological sciences and to medicine. This revolution is enabled by the convergence of an array of technologies and medical and social practices that offer unprecedented opportunities for innovative approaches to medical practice and to life science research. The vision driving the Engineering for Health (E4H) Center of Institut Polytechnique de Paris (IP Paris) is that seizing these opportunities and realizing their full potential requires a highly interdisciplinary approach where quantitative and social scientists collaborate closely with the life science and medical communities.
Key figures
- 5 Engineering IP Paris schools
- 10 IP Paris departments
- 23 Laboratories
- 250 Research and support staff
- 5 Scientific and technological platforms
- 6 Specialized study tracks
Mission
The goal of the Engineering for Health (E4H) Interdisciplinary Research Center is to leverage IP Paris’ strengths in the physical, mathematical, and social sciences towards a highly quantitative and interdisciplinary approach to the life sciences and medicine. We wish to foster a dynamic environment where basic and translational research continuously feed off of one another to address major societal challenges in health and well-being.
How we accomplish our mission
- The E4H Center plays an integral role in fostering research, training, and innovation. IP Paris has significant strengths and world-class research activities in interdisciplinary life science research with more than 100 faculty members and their teams from all ten IP Paris academic departments pursuing a broad range of fundamental and applied studies. The existing research and training programs within the IP Paris community provide a unique opportunity for tackling key societal challenges and associated grand scientific questions through a highly interdisciplinary approach. By focusing on research aimed at understanding, imaging, modeling, predicting, and engineering living systems and by creating a strongly-knit community, the E4H Center serves to significantly amplify the global scientific impact of IP Paris research in this area.
- A critical mission of the E4H Center is the training and mentoring of young scientists. By virtue of its outstanding academic reputation and its highly selective admissions process, IP Paris attracts not only many of France’s top students and young scientists but also outstanding students and postdoctoral fellows from around the world. The E4H Center is affiliated with the Interdisciplinary Biology, Biomedical Engineering, and Mathematics for Living Systems PhD programs (graduate school and PhD Track) and thus provides state-of-the-art training in fields critical for life sciences and health.
- IP Paris is an ideal environment for innovation, technology transfer, and translational research with a fully staffed technology transfer office and a startup incubator and accelerator on campus. New fully equipped space and laboratories are available for students, startup companies, and industrial partners working on various bioengineering design and development projects. Ongoing collaborations with clinicians and partner institutes provide ample opportunities for translational research, most notably in personalized (patient-specific) therapies, medical device design and development, and connected health products.
Founding members
Research in the E4H Center spans the spectrum of highly fundamental studies all the way to applied and translational investigations. It also spans a wide spectrum of scales ranging from the molecular to the population level. Our research activities can be broadly categorized as follows:
Development of a fundamental quantitative understanding of living systems, including prokaryotes, and ranging from the molecular to the macroscopic scales. This includes biochemistry and biophysics of biomolecules, genomics and transcriptomics, basic principles in cell and developmental biology and biophysics, and systems biology and physiology.
Imaging molecules, cells, tissues, and whole organisms using a variety of imaging modalities including NMR, crystallography, and electron microscopy. A particular campus strength is the development of novel approaches in biophotonics and advanced optical imaging techniques (super-resolution, in-depth, high-throughput, and multimodal). Cellular/molecular imaging as well as genomic/proteomic studies generate large amounts of data, thereby creating considerable opportunities in data science, machine/deep learning, quantification, and analysis.
Multiscale modeling approaches focusing on molecular modeling of RNA and protein structure, in silico design of therapeutic molecules, and modeling of the structure and function of various organs and multi-organ systems in health and disease. In parallel, mathematical approaches in population dynamics are applied towards a predictive framework for the emergence of zoonoses and pathogen mutations.
Knowledge gained from the first three research directions above serves as a basis for translational activities in biomedical engineering. An example is the development of organ-on-chip/disease-on-chip systems that are used for designing therapeutic molecules/vaccines and for screening drugs. Particular emphasis is placed on emerging threats (e.g. viruses and antibiotic resistance) as well as personalized medicine (individual patient monitoring, ‘omic’ approaches, bioinformatics, machine learning, and predictive modeling). Synthetic biology, which encompasses methodologies from various disciplines including biophysics, chemical and biological engineering, and computer science, is used as a basis for designing new biological systems and interfacing with novel biomedical devices.
A critical mission of the E4H Center is the training and mentoring of young scientists at the doctoral and postdoctoral levels. By virtue of its outstanding academic reputation and its highly selective admissions process, IP Paris attracts many of France’s top engineering students as well as excellent doctoral students and postdoctoral fellows from around the world with strong and rigorous training in the physical and mathematical sciences. A significant fraction of these bright young scientists are interested in applying their skills to the life sciences and healthcare fields. The E4H Center provides the ideal training and mentoring environment for these scientists.
Our training courses
- 1 PhD Track: Bioengineering and Quantitative Life Sciences
- 4 Masters:
- Specialized Engineer Diploma: General engineer in digital health track
- 1 Short training program : Innovation and entrepreneurship in the MedTech-BioTech field
The E4H Interdisciplinary Centre supports your biomedical engineering projects through calls for projects:
Serge Schoen New Synergies Grant Program | Deadline: February 16, 2025 |
Medical Fellows Program | Deadline: January 13, 2025 |
Postdoctoral Fellowship Program | Deadline: January 13, 2025 |
BME Student International Experience Program | Permanent call (see deadlines) |
BME Conference Fellowships Program | Permanent call (see deadlines) |
BME Design Projects | Closed on September 20, 2024 |
BME Pedagogical Seed Grants | Closed on May 12, 2024 |
BME Seed Grants | Call closed on April 18, 2023 |
February 7, 2025 | AMR Seminar: Interdisciplinary approaches to antimicrobial resistance |
Novembre 22, 2024 | Biology PhD Day 2024 |
November 6, 2024 | E4H Annual Forum 2024 |
15 october 2024 | Workshop Biology of Cancer Cells |
June 20, 2024 | Séminaire Polytechnique Santé #6 |
May 28, 2024 | Séminaire Polytechnique Santé #5 |
14 Mai 2024 | Rencontres Innovation Santé #2 |
22 mars 2024 | Inauguration of the BME Student Club of IP Paris |
30 November 2023 | Rencontres Innovation Santé #1 |
9 novembre 2023 | Séminaire : Approches interdisciplinaires face aux résistances aux antimicrobiens |
5 July 2023 | Annual Forum E4H |
13 April 2023 | Biomedical Engineer Master Open Day |
14 March 2023 | Symposium on Engineering for Cardiovascular Health |
17 February 2023 | Lancement du LivingLab |
11 october 2022 | Workshop: Current Trends in Cancer Modeling and Research |
7 July 2022 | E4H Annual Forum |
To keep up to date with job and internship offers from the IP Paris life sciences and health community and its partners in France and abroad, subscribe to our newsletter:
> Subscribe
- Abdul Barakat, Scientific Co-Director
- Jean-Louis Mergny, Scientific Co-Director
- Silvia Corsini, Chief Operation Officer
- Delphine L'Huillier, Administrative and financial Officer
- Joni Frederick, E4H Platform Manager
- Benoît Monégier du Sorbier, Communication and Partnerships Manager
- Abdul Barakat, École polytechnique
- Jean-Louis Mergny, École polytechnique
- Jocelyne Arquembourg, Télécom Paris
- Elsa Angelini, Télécom Paris
- Jerome Boudy, Télécom SudParis
- Dominique Chapelle, Inria, École polytechnique
- Philippe Choné, ENSAE
- Jean Boisson, ENSTA Paris
- François Hache, École polytechnique
- Sylvie Méléard, École polytechnique
- Anne Chantal Gouget, École polytechnique
- Angelo Pierangelo, École polytechnique
- Yann Ponty, École polytechnique
Engineering for Health
X Novation Center, École polytechnique
Avenue Coriolis
91120 Palaiseau
Our society is undergoing a revolution that will fundamentally redefine our approach to the biological sciences and to medicine. This revolution is enabled by the convergence of an array of technologies and medical and social practices that offer unprecedented opportunities for innovative approaches to medical practice and to life science research. The vision driving the Engineering for Health (E4H) Center of Institut Polytechnique de Paris (IP Paris) is that seizing these opportunities and realizing their full potential requires a highly interdisciplinary approach where quantitative and social scientists collaborate closely with the life science and medical communities.
Key figures
- 5 Engineering IP Paris schools
- 10 IP Paris departments
- 23 Laboratories
- 250 Research and support staff
- 5 Scientific and technological platforms
- 6 Specialized study tracks
Mission
The goal of the Engineering for Health (E4H) Interdisciplinary Research Center is to leverage IP Paris’ strengths in the physical, mathematical, and social sciences towards a highly quantitative and interdisciplinary approach to the life sciences and medicine. We wish to foster a dynamic environment where basic and translational research continuously feed off of one another to address major societal challenges in health and well-being.
How we accomplish our mission
- The E4H Center plays an integral role in fostering research, training, and innovation. IP Paris has significant strengths and world-class research activities in interdisciplinary life science research with more than 100 faculty members and their teams from all ten IP Paris academic departments pursuing a broad range of fundamental and applied studies. The existing research and training programs within the IP Paris community provide a unique opportunity for tackling key societal challenges and associated grand scientific questions through a highly interdisciplinary approach. By focusing on research aimed at understanding, imaging, modeling, predicting, and engineering living systems and by creating a strongly-knit community, the E4H Center serves to significantly amplify the global scientific impact of IP Paris research in this area.
- A critical mission of the E4H Center is the training and mentoring of young scientists. By virtue of its outstanding academic reputation and its highly selective admissions process, IP Paris attracts not only many of France’s top students and young scientists but also outstanding students and postdoctoral fellows from around the world. The E4H Center is affiliated with the Interdisciplinary Biology, Biomedical Engineering, and Mathematics for Living Systems PhD programs (graduate school and PhD Track) and thus provides state-of-the-art training in fields critical for life sciences and health.
- IP Paris is an ideal environment for innovation, technology transfer, and translational research with a fully staffed technology transfer office and a startup incubator and accelerator on campus. New fully equipped space and laboratories are available for students, startup companies, and industrial partners working on various bioengineering design and development projects. Ongoing collaborations with clinicians and partner institutes provide ample opportunities for translational research, most notably in personalized (patient-specific) therapies, medical device design and development, and connected health products.
Founding members
Research in the E4H Center spans the spectrum of highly fundamental studies all the way to applied and translational investigations. It also spans a wide spectrum of scales ranging from the molecular to the population level. Our research activities can be broadly categorized as follows:
Development of a fundamental quantitative understanding of living systems, including prokaryotes, and ranging from the molecular to the macroscopic scales. This includes biochemistry and biophysics of biomolecules, genomics and transcriptomics, basic principles in cell and developmental biology and biophysics, and systems biology and physiology.
Imaging molecules, cells, tissues, and whole organisms using a variety of imaging modalities including NMR, crystallography, and electron microscopy. A particular campus strength is the development of novel approaches in biophotonics and advanced optical imaging techniques (super-resolution, in-depth, high-throughput, and multimodal). Cellular/molecular imaging as well as genomic/proteomic studies generate large amounts of data, thereby creating considerable opportunities in data science, machine/deep learning, quantification, and analysis.
Multiscale modeling approaches focusing on molecular modeling of RNA and protein structure, in silico design of therapeutic molecules, and modeling of the structure and function of various organs and multi-organ systems in health and disease. In parallel, mathematical approaches in population dynamics are applied towards a predictive framework for the emergence of zoonoses and pathogen mutations.
Knowledge gained from the first three research directions above serves as a basis for translational activities in biomedical engineering. An example is the development of organ-on-chip/disease-on-chip systems that are used for designing therapeutic molecules/vaccines and for screening drugs. Particular emphasis is placed on emerging threats (e.g. viruses and antibiotic resistance) as well as personalized medicine (individual patient monitoring, ‘omic’ approaches, bioinformatics, machine learning, and predictive modeling). Synthetic biology, which encompasses methodologies from various disciplines including biophysics, chemical and biological engineering, and computer science, is used as a basis for designing new biological systems and interfacing with novel biomedical devices.
A critical mission of the E4H Center is the training and mentoring of young scientists at the doctoral and postdoctoral levels. By virtue of its outstanding academic reputation and its highly selective admissions process, IP Paris attracts many of France’s top engineering students as well as excellent doctoral students and postdoctoral fellows from around the world with strong and rigorous training in the physical and mathematical sciences. A significant fraction of these bright young scientists are interested in applying their skills to the life sciences and healthcare fields. The E4H Center provides the ideal training and mentoring environment for these scientists.
Our training courses
- 1 PhD Track: Bioengineering and Quantitative Life Sciences
- 4 Masters:
- Specialized Engineer Diploma: General engineer in digital health track
- 1 Short training program : Innovation and entrepreneurship in the MedTech-BioTech field
The E4H Interdisciplinary Centre supports your biomedical engineering projects through calls for projects:
Serge Schoen New Synergies Grant Program | Deadline: February 16, 2025 |
Medical Fellows Program | Deadline: January 13, 2025 |
Postdoctoral Fellowship Program | Deadline: January 13, 2025 |
BME Student International Experience Program | Permanent call (see deadlines) |
BME Conference Fellowships Program | Permanent call (see deadlines) |
BME Design Projects | Closed on September 20, 2024 |
BME Pedagogical Seed Grants | Closed on May 12, 2024 |
BME Seed Grants | Call closed on April 18, 2023 |
February 7, 2025 | AMR Seminar: Interdisciplinary approaches to antimicrobial resistance |
Novembre 22, 2024 | Biology PhD Day 2024 |
November 6, 2024 | E4H Annual Forum 2024 |
15 october 2024 | Workshop Biology of Cancer Cells |
June 20, 2024 | Séminaire Polytechnique Santé #6 |
May 28, 2024 | Séminaire Polytechnique Santé #5 |
14 Mai 2024 | Rencontres Innovation Santé #2 |
22 mars 2024 | Inauguration of the BME Student Club of IP Paris |
30 November 2023 | Rencontres Innovation Santé #1 |
9 novembre 2023 | Séminaire : Approches interdisciplinaires face aux résistances aux antimicrobiens |
5 July 2023 | Annual Forum E4H |
13 April 2023 | Biomedical Engineer Master Open Day |
14 March 2023 | Symposium on Engineering for Cardiovascular Health |
17 February 2023 | Lancement du LivingLab |
11 october 2022 | Workshop: Current Trends in Cancer Modeling and Research |
7 July 2022 | E4H Annual Forum |
To keep up to date with job and internship offers from the IP Paris life sciences and health community and its partners in France and abroad, subscribe to our newsletter:
> Subscribe
- Abdul Barakat, Scientific Co-Director
- Jean-Louis Mergny, Scientific Co-Director
- Silvia Corsini, Chief Operation Officer
- Delphine L'Huillier, Administrative and financial Officer
- Joni Frederick, E4H Platform Manager
- Benoît Monégier du Sorbier, Communication and Partnerships Manager
- Abdul Barakat, École polytechnique
- Jean-Louis Mergny, École polytechnique
- Jocelyne Arquembourg, Télécom Paris
- Elsa Angelini, Télécom Paris
- Jerome Boudy, Télécom SudParis
- Dominique Chapelle, Inria, École polytechnique
- Philippe Choné, ENSAE
- Jean Boisson, ENSTA Paris
- François Hache, École polytechnique
- Sylvie Méléard, École polytechnique
- Anne Chantal Gouget, École polytechnique
- Angelo Pierangelo, École polytechnique
- Yann Ponty, École polytechnique
Engineering for Health
X Novation Center, École polytechnique
Avenue Coriolis
91120 Palaiseau