FastGlide

The project FastGlide was a 2024 winner of the PREMATURATION call for projects, led by the Innovation Lab of IP Paris.

Medical diagnostic techniques often rely on high resolution microscopy image analysis. However, current slide scanners are time-consuming, costly, require high mechanical precision and deliver images with varying image quality across its field of view. As a result, these technologies are not well suited for clinical use.

FastGlide is a non-mechanical, time-efficient, cost-effective and label-free technique that provides access to enriched, high resolution, controlled high-quality images—making microbiological analysis accessible to a much broader market. Furthermore, through virtualization, samples can be saved and stored for subsequent analysis.

The developed technology is based on Fourier Ptychographic Microscopy (FPM) combined with specific reconstruction algorithms to correct local optical aberrations such as defocus aberrations.

In FPM, the sample is imaged under different illumination conditions, and an inverse problem-solving algorithm is applied to reconstruct a super-resolved image.

High throughput WSI scanner

• Extended field of view (25x-100x)
• Extended depth of field (10x)

Quantitative imaging

• Enriched RGB images with access to intensity and phase modalities
• High resolution (150nm)
• Compensation of optical aberrations
• Label-free imaging

Others 

• Compact and cost effective solution with limited mechanics
• Complete sample virtualization
• Possible integration to existing setup (microscopy, Raman spectroscopy)